What next?

Welcome. There are so many variables there are simply no easy answers. Plus, everyone is different on how ther body reacts. It may even be a time for a set of fresh eyes with a second opinion. Just make sure it is a bladder specialty center/teaching facility like an MD Anderson etc.

Sorry that I was not able to respond promptly. Believe it or not. We had a Board meeting for the American Bladder Cancer Society this afternoon.

Afraid that no one can really answer your question. Anything abnormal in the bladder needs to be examined. Both irritation and bladder cancer can look different depending on the location and type. Wish I could be of more help, but this is why they do biopsies.

Sara Anne

First, irritation from BCG is quite common (often called BCG-cystitis.) So it is likely that this is what your father has.
However, it DOES need to be checked out.

If it should be a return of the CIS, and there is no evidence of a spread into the muscle, a second trial of BCG or BCG with interferon is often effective, avoiding a radical cystectomy. However, if the second trial does not work a cystectomy can be life saving.

Here's hoping it is a BCG effect!!!

Sara Anne