Well, I am NOT a pathologist, but here is how I would interpret that...There are areas that are not normal with strange looking cells (the "dysplasia") AND areas within that that show definite features of CIS. When I was diagnosed, the first biopsy showed "areas of dysplasia." So the uro went back in and took more samples and the result was CIS.
CIS is kind of like a rash on the bladder lining....a thin layer of malignant cells rather than a lumpy tumor. So I suspect that there are areas where the cells show definite properties that CIS cells do and around that areas where there are sort of non-specific abnormalities, but not quite CIS.
Does that muddy it all up or make it clearer?
Diagnosis 2-08 Small papillary TCC; CIS
BCG; BCG maintenance
Vice-President, American Bladder Cancer Society