Reaction to BCG

15 years 1 month ago #24554 by Alan
Replied by Alan on topic Reaction to BCG

DX 5/6/2008 TAG3 papillary tumor .5 CM in size. 2 TURBS followed by 6 instillations of BCG weekly with a second round of 6 after a 6 week wait.

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15 years 1 month ago #24491 by Moonerj
Replied by Moonerj on topic Reaction to BCG
I wonder if they are trying different mixtures to different patients.
Very interesting. This has really got my attention now.
Thanks Pat,:huh:
Jack

TA Grade 1
3 Turbts
30 BCG Treatments
Cancer Free since Nov 2007

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15 years 1 month ago - 15 years 1 month ago #24490 by Patricia
Replied by Patricia on topic Reaction to BCG
Double Blind......
en.wikipedia.org/wiki/Randomized_controlled_trial#Double-blind_trial
Pat
you'll have to copy and paste as the entire site is not highlighted....?

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15 years 1 month ago #24479 by Moonerj
Replied by Moonerj on topic Reaction to BCG
Hi Orpheus

Pat has done a great job of explaining the wash.
The trial is only being conducted on patients,that have continued to fail BCG.

www.bioniche.com/research_trials.cfm

Jack

TA Grade 1
3 Turbts
30 BCG Treatments
Cancer Free since Nov 2007

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15 years 1 month ago #24478 by Moonerj
Replied by Moonerj on topic Reaction to BCG
Hi, Pat

I know that I would be receiving Urocidin. I am not sure what the double blind means. I read that also, but after I had received noitification, I would be acceppted in Phase 111. I was too late for Phase 11.
I will try to find out from Dr. Jewitt's assistant when I return from vacation. As you know I am hoping I do not need to be involved in this trial.
Thanks for your interest.
Jack

TA Grade 1
3 Turbts
30 BCG Treatments
Cancer Free since Nov 2007

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15 years 1 month ago #24477 by Patricia
Replied by Patricia on topic Reaction to BCG
Hi Jack......just wondered about this trial as it is also recruiting here in the States at Hopkins, MSK, and MD Anderson. But as i understand it..it is a double blind trial......does that mean you may not receive the Urocidin?
The trial will enrol approximately 800 patients and is a double-blind, randomized trial.

About MCC

MCC is a sterile mycobacterial cell wall-DNA complex composition that has a dual mode of action: immune stimulation and direct anticancer activity. It is formulated as Urocidin(TM) for the treatment of bladder cancer, where it is administered by trans-urethral catheter directly into the bladder, coming into contact with immune system cells and bladder cancer cells. MCC is undergoing preclinical evaluation as a treatment for peritoneal carcinomatosis associated with colon and ovarian cancer
Just curious........Pat

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