Clear Urine Cytology Test

15 years 7 months ago - 15 years 7 months ago #20437 by Rosemary
Replied by Rosemary on topic Clear Urine Cytology Test
David,

Which test are you getting, the NMP22 or the Urine Cytology? I've been reading about NMP22, and it seems to me that this is the most ultrasensitive test, AND it can be performed IN HOUSE.

There does seem to be a differential in whether it picks up high or low grade.
And from some of the things that I have read, it sounds like the urine cytology is no better than a cystoscopy alone....

I tell you, I try really hard, but, I do stay confused..
Still, I do feel glad about the results, and as far as trusting my doctor to do the right thing, well, as they say, "No news is good news."

Good to hear from you. Hope you are doing well.

Ro

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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15 years 7 months ago #20436 by ddoyle
Replied by ddoyle on topic Clear Urine Cytology Test
Rosemary,

Your info on the reliability (or lack thereof) of urine cytology comes as no surprise. Mine have always been negative and invariably the next cysto finds papillary tumors.

Good news about your test, though.

Best wishes,

Your friend,

David

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15 years 7 months ago #20426 by maxmag
Replied by maxmag on topic Clear Urine Cytology Test
Hi Rosemary,
Glad to hear things are going well for you.

Regarding this subject,How does the "Urovision" test
fit into all of this?
Stay well,
Max

Max
Age 70
Ta G2
Dx March 2007

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15 years 7 months ago #20245 by Rockyiss
Replied by Rockyiss on topic Clear Urine Cytology Test
Rosemary, Glad your test came out OK ! It is always a good day when the results are neg. Rocky

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15 years 7 months ago #20215 by Rosemary
Replied by Rosemary on topic Clear Urine Cytology Test
Thanks, Nix.:)

I'm learning more about this disease every day!!

Also, I failed to mention, that combining a urine cytology or NMP22 is more effective at detecting recurrance than a cystoscopy alone.

The primary source for the following information is attributed to the Journal of the American Medical Association and can be found here:

www.medpagetoday.com/HematologyOncology/OtherCancers/tb/2506

In a prospective cross-sectional study, the BladderChek test, combined with a cystoscopic examination, detected 99% of all recurrent cancers, according to H. Barton Grossman, M.D., of the M.D. Anderson Cancer Center.


Also, the test alone detected eight of nine cancers that were not found during initial cystoscopy, Dr. Grossman and colleagues reported in the Jan. 18 issue of the Journal of the American Medical Association.


By contrast, the standard urine cytology test, combined with cystoscopy, detected 94.2% of cancers - a rate of detection that was not significantly greater than that of cystoscopy alone, the researchers found.


The BladderChek test, manufactured by Matritech of Newton, Mass., detects elevated amounts of nuclear mitotic apparatus protein, or NMP22, which is released into urine during cell death.


Unlike standard urine cytology, the test for NMP22 does not require whole cancer cells and can be done in a physician's office while the patient waits. It is also cheaper than cytology, the researchers noted.

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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15 years 7 months ago #20209 by Nix
Replied by Nix on topic Clear Urine Cytology Test
thanks for the information, Rosemary. My cytology report has always come back negative, even when CIS was found. I am happy to see there are other tests to check. You always share such helpful information - thanks:)

Nancy S
Ta CIS
dx Ta 11/06
dx Ta CIS 10/07

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