As promised ...
Here are the two emails from Dr. Lamm
Your BC Buddy,,,
Yosarian the wordy.......
Below is the result of your feedback form. It was submitted by
(@hotmail.com) on Thursday, November 15, 2007 at 12:26:04
question: Subject: Timing of Cystoscopy and BCG dosage.
My husband had TURBT 4-20-07 by FL urologist.
Second TURBT 5-10-07 Sloan-Kettering by Herr (2nd opinion)
BCG in FL - 6 weeks 5/29-7/3
Cysto at Sloan- 8/13/07 all OK
BCG maintenance (3) at full strength in FL (8/22-9/5)
Cysto at Sloan - 11/12/07 All ok but identified one "area of redness" .
Urine test negative for cancer cells. Suggested 1/2 strength BCG. (Dr.
Herr agreed to let us have BCG) Our FL urologist seems reluctant to
reduce (or dosen't have staff that knows how. Last BCG (9/5)had most
severe side effects (fever 100 degrees, freq, urgency, lasting 1 week.
Next Cysto not for over 6 months. (6/2/07-at Sloan)
1) Should he have it in 3 months?
2) Should we insist BCG be reduced strength? 1/2, 1/3 ??? Thank you.
Your website is a godsend.
Submit: Submit Question
Date: Sat, 17 Nov 2007 19:54:21 -0800
> Subject: Re: Ask Dr. Lamm
> From: @bcgoncology.com
> To: @hotmail.com
>
> BCG Dose Reduction; 3 Week Maintenance BCG
> Dear Friend,
> Your husband's severe reaction to continued full strength BCG is just what
> is expected. ONly 16% of patients were able to take full strength BCG at
> each of the schedule 3 week maintenance periods. By reducing the dose to
> 1/3 (not 1/2), with subsequent reductions (1/10, 1/30, 1/100) we are able
> to get most patients through the entire program- even with extension to
> more than 10 years when needed. The dose of TheraCys BCG (Connaught)
> varies from 2 to 19 hundred million colony forming units per vial.
> Cutting the dose by half could easily keep the dose within the range of
> "full." It is not rocket science to reduce the dose. For 1/3, you take
> 16.6 ml of the 50 ml dilution. For 1/10th you take 5cc, and so on. I
> would not wait for 6 months for a follow up cystoscopy. The standard
> protocol is every 3 months for 2 years, every 6 months for 2 years, and
> then yearly for patients who have high risk (G3, T1 or CIS) disease.
> Check my website/lectures for the specifics on the schedule- and thank you
> for your compliment on our website- my son is our "webmaster."
> Best regards,
> Don Lamm, MD
> PS: Arizona is lovely this time of year.
> > Below is the result of your feedback form. It was submitted by
> >@hotmail.com) on Monday, March 3, 2008 at 10:15:40
> >
> >
> > question: Dear Dr. Lamm
> >
> > My husband (now 60 yrs old) was diagnosed with T1G3 Bladder Tumor (papillary
> > transitional cell carcinoma) in April 2007. He had a TURBT and then
> > Myomiticin treatment at that time and a subsequent TURBT (negative
> > pathology for cancer) by Dr. Herr in May of 2007. He completed the 6
> > initial BCG treatment by our Florida Urologist, with subsequent
> > cystoscopies at 3months (followed by 3 BCG), 6 months (followed by 2 BCG
> > due to severe reaction to cancel 3rd), and now at 9 months another
> > Cystoscopy and a biopsy on a suspicious area to confirm no cancer cells.
> > (Benign urothelium with reactive changes was the diagnosis.) All good.
> >
> > However, our urologist suggested since my husband has had no recurrence,
> > that he discontinue the BCG treatments (12 month) since: a) previous
> > severe reaction which means he would reduce to 1/10 strength. b) Dr. is
> > not aware that such a reduced dose has been shown to prevent future
> > recurrence. c) The BCG treatments create areas in the bladder that look
> > suspicious thus prompting new biopsies. He is suggesting continued
> > Cystoscopies to monitor for tumor recurrence and then IF, a recurrence is
> > diagnosed, begin BCG again.
> >
> > Our Florida Urologist knows we have been corresponding with you regarding
> > BCG and values your opinion. The next scheduled BCG would be after our 1
> > year Cystoscopy in June. Since he has had no recurrence since the initial
> > TURBT (4-20-07), would you recommend continuing BCG at 12,18, 24, 36
> > months (also taking Oncovite, garlic, pomegranate and selenium) or just be
> > religious in getting Cystoscopies every six months/or annually to monitor
> > for tumor recurrence? We appreciate all you have done for the BC
> > community with your website.
> >
> > Sincerely,
> >
> >, Florida
> >
> Date: Mon, 10 Mar 2008 20:39:58 -0700
> Subject: Re: Ask Dr. Lamm
> From: @bcgoncology.com
> To: @hotmail.com
>
> Why Use Maintenance BCG If There is No Recurrence?
> Dear Friend,
> G3T1 bladder cancer is a dangerous disease, and I strongly advocate
> maintenance therapy. Maintenance is by definition given to those who are
> free of recurrence. It appears to be required for reduction in the risk
> of progression, and significantly reduces recurrence compared with
> induction or short course BCG.
> That said, it is also important to avoid toxicity. That can quite easily
> be done by reducing the dose. Can we say for sure that the "reduced dose"
> maintenance is effective? Not with randomized studies, but certainly with
> logic and experience- it works!
> Best regards,
> Don Lamm, MD
During the war an Italian girl saved my life. She hid me in her basement in Cleveland.
A priest is sent to Alaska. A bishop goes up to visit one year later. The bishop asks, "How do you like it up here?" The priest says, "If it wasn't for my Rosary, and 2 martinis a day, I'd be lost. Bishop, would you like a martini?" "Yes." "Rosary, get the bishop a martini!"
A guy says, "I'm so old that I forgot how old I am." An old woman says, "I'll tell you how old you are. Take off your clothes and bend over." The man does this. The woman says, "You're seventy four." The man says, "How can you tell?" The woman says, "You told me yesterday."