Here are some brief explanations from our FACTS section in About Bladder Cancer on the Home Page
bladdercancersupport.org/information/staging-and-grading-pathology-bladder-cancer.html
bladdercancersupport.org/diagnoses/carcinoma-in-situ-cis-of-the-urinary-bladder.html
Simply put, carcinoma in situ (CIS) of the bladder is a form of cancer that appears as a rash on the surface of the bladder rather than as a solid discrete tumor,. It is always high grade, which means that it is fast-growing and can spread rapidly, but if found early is often well treated by a form of immunotherapy, BCG.
Have you had a TURB (biopsy) of the bladder? While the FISH test is very sensitive, sometimes it is too much so and can show false positive results. It is only when the diagnosis is confirmed by a biopsy and pathology examination that you can be sure of the diagnosis.
I am a good example of a patient with CIS. Was diagnosed in 2008 and had BCG treatments and maintenance. I have been cancer=free ever since!!!
Sara Anne