BCG seems to affect everybody differently
I had most of my discomfort and side effects with treatment 3 of my initial 6, and with my first set of 3 maintenance treatments. With each BCG treatment, I had a variety of side effects (flu-ish, urgency, etc) for the first 12-24 hours after each treatment, but most of the issues subsided within the 12-24 hours. I also have had some joint pains since my first set of maintenance treatments, but luckily the pains/discomfort did not get any worse with my second set of maintenance treatments. For my second set of maintenance treatments, I was more proactive. I took some Advil before I went for the treatment, and I took AZO about 30 minutes before I voided the BCG. I also started drinking my water about 20 minutes before my first void, so that the BCG was diluted some when my 2 hour hold time was up. That seemed to work for me. I still had some feelings of urgency and 'peeing razor blades' for a few hours, but it wasn't any where near as bad as it was for my first set of 3 maintenance treatments. So far, all of my treatments have been at full strength.
Take care and keep us posted,
LillianG