I've only been around here for a short time, but my urologists wanted everything healed inside my bladder before any BCG treatments. Before being treated at Cancer Treatment Centers of America (CTCA), I had one BCG in a doctors office, told to go home, hold the BCG in, roll from side to side, back to front for 15 minutes each for a total of 2 hours and then urinate. I was also told to increase my water intake. This BCG treatment was the worst after effects I had and I think it was the drive home, letting the BCG sit in the bottom of my bladder. My 2nd of 6 treatments and my 1st 3 week maintenance were at CTCA. They keep you at the Hospital, do everything methodical, step by step and monitor you for the 3 hours from beginning to end. You have lab work before hand, prep, the instillation and make sure you are fine afterwards. There have been several examples of BCG treatments, but I do know my first BCG treatment was not what I wanted again. Good luck, Jay