Question on path report

16 years 3 months ago #12328 by Rosemary
Replied by Rosemary on topic Question on path report
Dnile,

We have had a lot of confusing discussion around this forum about CIS. My patholgy states that I have Cancer in Situ, but, I do not have CIS. Someone here tried to persuade me that I have CIS, when I do not have CIS!!

From my research, it seems that "in-situ" is a term that means "in place".

Like Wendy said, it is very good that you do not have a tumor involved in your pathology report.

I did not mean to sound brusque in my reply to you. I am sorry if it came off that way.

Hi, Wendy!!

Rosemary

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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16 years 3 months ago #12326 by wendy
Replied by wendy on topic Question on path report
Hi,

CIS is considered a friendly form of cancer except when it's bladder cancer. I'm sorry to say. But it is still non-muscle invasive. For the rest, your path report is pretty good. I wonder if there was any other tumor found? CIS almost always shows up along side papillary tumors (the most common sort) and is actually rare, only 10% of diagnoses. And only 1% of the time does CIS appear alone in the bladder. If that is what you really have, it is considered to be less aggressive than the type of bladder CIS that appears alongside the other tumor types (there are many different forms of bladder cancer).

You can read more about it here:
blcwebcafe.org/superficialblca.asp

CIS is almost always given BCG as the first line treatment because it works very well, eradicating it about 75% of the time. But as we know too well, blc tends to have a high recurrence rate so you will need close follow up for life. But rest assured you can still live a very long life post diagnosis, and die of old age. It happens!
Wendy

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16 years 3 months ago #12323 by Imndnile
Replied by Imndnile on topic Question on path report
I didnt say anyone here would say that, I was being a smart ass to the first responders answer because I did not ask what CIS was. My question is why does my Path report say Urothelial ductal carcinoma in situ...

Which when I googled this diagnosis it comes up as Breast cancer. If this so then maybe they have made a mistake.
Diagnosis:

A. Bladder Biopsy:
1. Urothelial ductal carcinoma in situ

Imndnile no more.
DX: TIS (CIS): Carcinoma in situ (non-invasive flat high-grade (G3) cancer)
12/13/07

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16 years 3 months ago #12293 by Rosemary
Replied by Rosemary on topic Question on path report
Dear Dnile,

CIS is a very dangerous and unstable condition of the bladder and can progress stealthily into an untreatable cancer.

CIS must be monitored and treated.

No one here will tell you that the doctor is trying to take your money.

Rosemary

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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16 years 3 months ago #12292 by Imndnile
Replied by Imndnile on topic Question on path report

So what they are saying here this is not cancer. It may or may not progress to cancer? Should they not wait and say do another look in a year or so. to see if it really is something?
It seems if what they say here is true ("cancer that may, if left untreated long enough, transform into a malignant neoplasm") then the doctor is just trying rack up so cash at my exspense and put me through needless pain and suffering. I think I might just cancel those appointments for the BCG. Thanks for the advise

Imndnile no more.
DX: TIS (CIS): Carcinoma in situ (non-invasive flat high-grade (G3) cancer)
12/13/07

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16 years 3 months ago #12253 by Kim
Replied by Kim on topic Question on path report
Hello Imndnile, This is Wikipedia's definition....

Carcinoma in situ (CIS) is an early form of carcinoma defined by the absence of invasion of surrounding tissues. In other words, the neoplastic cells proliferate in their normal habitat, hence the name 'in situ' (Latin for 'in its place'). For example, carcinoma in situ of the skin, also called Bowen's disease is the accumulation of neoplastic epidermal cells within the epidermis only.

For this reason, CIS will usually not form a tumor. Rather, the lesion is flat (in the skin, cervix, etc) or follows the existing architecture of the organ (in the breast, lung, etc). Some CIS, however, form tumors, for example colon polyps or papillary cancer of the bladder.

Many forms of invasive carcinoma (the most common form of cancer) originate from a CIS lesion. Therefore, CIS is considered a precursor or incipient form of cancer that may, if left untreated long enough, transform into a malignant neoplasm.

When explaining a laboratory report to a patient, most doctors will refer to CIS as pre-cancer, not cancer. However, because most forms of CIS have a real potential to turn into invasive carcinoma, doctors will usually recommend that the lesion be completely removed. Therefore, CIS is usually treated much the same way as a malignant tumor.

In the TNM classification, carcinoma in situ is indicated as TisN0M0 (Stage 0).

Take Care, Kim

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