Tough one...figures are not great for recurrent CIS
Consider patients with recurrent CIS for an early cystectomy. At 5 and 10 years, approximately 70% and 30% of patients with CIS who are treated with BCG are disease free, respectively. Recurrent CIS, despite intravesical BCG, is associated with a 63% risk of progression to muscle-invasive bladder cancer. Recurrence after BCG treatment also may occur in the upper urinary tract or prostatic urethra.
Vanderbilt is a great institution for bladder cancer. Its easy for me to say get rid of the bladder because i don't have one...but then i don't miss it one bit either.
Pat